Uplizna (inebilizumab-cdon) is an FDA-approved prescription infusion therapy used to treat certain autoimmune conditions, including NMOSD, IgG4-RD, and generalized myasthenia gravis (gMG).
You will be observed during your infusion and for at least 1 hour after each UPLIZNA infusion for warning signs and symptoms of an infusion reaction. Schedule your session today at Scottsdale Rheumatology Center and take the first step toward a personalized treatment plan with Uplizna treatment.
Our experienced team provides physician-supervised care, checks your diagnosis, and monitors you through every step of treatment—from insurance coordination support to infusion scheduling. So you can initiate Uplizna treatment with confidence. Flexible scheduling options and patient-focused care help ensure a smooth treatment experience designed to support your quality of life.
Inebilizumab (sold as Uplizna) is a CD19-directed cytolytic monoclonal antibody used to treat neuromyelitis optica spectrum disorder (NMOSD), IgG4-related disease (IgG4-RD), and generalized myasthenia gravis (gMG). It works by targeting specific B cells involved in autoimmune disease activity, helping reduce the risk of relapses. Uplizna is administered through intravenous (IV) infusion under medical supervision in a hospital or infusion clinic setting.
Uplizna is approved for the treatment of certain adults with: Neuromyelitis optica spectrum disorder (NMOSD), generalized myasthenia gravis (gMG), IgG4-related disease (IgG4-RD), or anti-muscle-specific tyrosine kinase (MuSK) antibody positive.The safety and effectiveness of Uplizna in pediatric patients have not been established.
Neuromyelitis Optica Spectrum Disorder: Neuromyelitis Optica Spectrum Disorder (NMOSD) is used to reduce the risk of relapsing attacks in adults with anti-AQP4 antibodies. NMOSD treatment centers on managing severe attacks with high-dose corticosteroids or plasma interchange (PLEX), followed by long-term immunotherapy (e.g., eculizumab, inebilizumab, satralizumab, or rituximab) to avoid relapses. Timely diagnosis is critical to escape permanent harm to the optic nerve and spinal cord.
Uplizna IgG4: Uplizna IgG4 is a treatment for adults with active IgG4-RD. It targets and depletes CD19+ B cells to reduce the overactive immune response, causing tissue inflammation and fibrosis. It works by reducing B cells to decrease immune-mediated swelling, meaningfully decreasing disease flares.
Generalized myasthenia gravis (gMG): Generalized myasthenia gravis (gMG) is an autoimmune condition that affects communication between nerves and muscles, leading to muscle weakness.
Uplizna works by targeting CD19-positive B cells, which play a role in autoimmune diseases. By reducing these cells, Uplizna helps decrease harmful immune system activity and may lower the risk of disease relapses.
Throughout your Uplizna infusion appointment, you’ll get pre-medications to decrease reaction danger, followed by a gentle IV infusion in an easy, supervised location. The infusion appointment may last several hours, including preparation and post-infusion monitoring. After the infusion, you’ll remain under observation for at least one hour to confirm safety. Some patients experience mild side effects like pain or fatigue. Most people can return home the same day with guidance for follow-up care.
Your treatment journey begins with a comprehensive consultation with our rheumatology team. We carefully evaluate your symptoms, review your medical history, and confirm your diagnosis.
2. Pre-Treatment TestingBefore initial therapy, we conduct vital lab investigations and screenings to maintain your safety. This may include blood tests and infection screening to help create a personalized treatment plan based on your medical needs.
3. Infusion SessionUplizna is managed through a measured intravenous (IV) infusion in our up-to-date infusion center. The early treatment consists of two doses prearranged two weeks apart, followed by planned infusions every six months. Our experienced staff is committed to providing a comfortable and supportive treatment experience.
4. Monitoring & Follow-UpYour protection is our priority. You will be carefully monitored throughout the infusion and for at least one hour afterward to look out for any reactions. Constant follow-ups help us track your progress, manage side effects, and improve your infusion therapy results.
Treatment costs vary based on insurance coverage, treatment plans, and eligibility for financial assistance programs
Here is the list of people who need Uplizna and Uplizna eligibility:
When searching for a reliable rheumatologist in Scottsdale or infusion therapy in Scottsdale, choosing the right clinic can make all the difference in your treatment experience and results.
Experienced Rheumatology SpecialistsOur clinic is led by experienced rheumatology specialists with widespread experience in treating complex autoimmune and inflammatory conditions. We stay up to date with the modern innovations in biologic therapies and infusion treatments to make sure you receive the most effective care offered.
Advanced Infusion CenterWe offer a comfortable infusion therapy center in Scottsdale. Our infusion center is designed with patient comfort, safety, and convenience in mind. Our expert nursing staff carefully monitors every infusion, ensuring a safe and stress-free experience throughout.
Personalized Care ApproachEvery patient’s condition is unique. That’s why we create personalized treatment plans based on your diagnosis, symptoms, and healthcare goals. We prioritize clear communication and concerned care.
If you are considering Uplizna infusion therapy in Scottsdale, our team is here to help; Scottsdale Rheumatology Center offers physician-supervised infusion therapy tailored to each patient's needs.
Specialized Uplizna Infusion CareWe provide Uplizna infusions for eligible patients while following strict safety protocols and personalized treatment plans.
Expert Monitoring & SupportFrom your initial consultation through post-infusion monitoring, our team ensures every step of your treatment is handled with care. We also assist with insurance approvals and available financial assistance programs.
Convenient Scottsdale LocationOur comfortable infusion center is designed to provide a safe, efficient, and supportive treatment environment.
Book an AppointmentSecure your session and infusion treatment at a time that suits you. Book your consultation or infusion appointment online: https://www.tebra.com/care/provider/mian-rizwan-md-1437380276
Uplizna is a prescription medication used to treat adults with certain autoimmune conditions, including neuromyelitis optica spectrum disorder (NMOSD), immunoglobulin G4-related disease (IgG4-RD), and generalized myasthenia gravis (gMG).
2. Is Uplizna safe?Uplizna is generally well tolerated when administered under medical supervision. Like other biologic therapies, it may cause side effects such as headache or fatigue, and patients are closely monitored during treatment to manage any potential risks.
3. How long does the Uplizna infusion take?Each Uplizna infusion typically takes about 90 minutes. Including preparation and post-infusion monitoring, the full appointment may last approximately 2.5 to 4 hours.
